Gear / rotor pumps do not "Cavitate" indepenently. If they suck an "air bubble", they can have a difficult time recovering.
The thread re; Gen III oiling on the Viper Club of America is excellent. The simple, primary issue is Cavitation. (Sucking an air bubble). Either under hard acceleration like SrtBrad stated or high cornering load (G-force). Our trucks are less likely due to deeper oil pan sump and overall less G-Forces. Keeping the oil level at the top end minimum or even just a bit over would be beneficial. I have personally went into a right hand bend with a slight downhill grade at well over a hundred and started braking mid corner. I sloshed enough oil that it came out my valve cover oil cap. Not only did it make a mess, I discovered that my cap o-ring was bad. It is amazing how much the oil moves around and defies gravity in these types of conditions.
Advanced Timing can cause "Pinging". Which is easy to hear and caused by ignition that just too early. Usually does not damage a piston.
Detonation is a monster. Super sonic sound wave caused by fuel mixture self igniting (Usually at the edge of a piston or a sharp edge like a valve relief cut out on piston top). These edges can glow red hot and promote detonation. Our combustion chamber design is not efficient (compare to a narrow angle 4 valve, aluminum, modern motorcycle engine) or flat. Poor quenching of the fuel mixture. You really want to squeeze the fuel mixture towards the center where the plug is (ours is off center).
The best remedie is keep the combustion chamber thermally stable (all aluminum engines like @200F) and give it as cool a charge as possible. An A/F ratio Under 12.6-1 NA is good insurance, I have commented plenty on using an AEM wideband to keep an eye on this. Torries SAFE tunes are smart!!
I would not say the design is "poor". But it looks like you can run into a limitation. Especially if you have a Viper car. Thier pan is shallower than ours.
The bearings themselves don't "spin" in the rod big end. However, if they loose the hydro dynamic barrier (from a passing air bubble), now they will get scored against the crank journal and melt away.
I do have a hard time with the crank shaft literally "flexing" in the block to an extent it overcomes the oil's "hydro dynamic barrier" under the flow and pressure from the pump. The blocks are so very ridged in design and have alot of "webbing" cast into them. The cranks themselves are Forged. I would love to see a block diagram of the engines oiling system to see some possible compromise in the oil feeds to the crank and rod journals.
If I had to take a stab at what happened to SrtDub's engine..... He had dreaded Detonation and or Cavitation. Most likely an lean tune combined with limitations mentioned by SrtBrad in the intake (Starved #3 cylinder) caused a lean condition. SrtDub did state that the pistons on cylinders 3+4 were tight on the rods. This would indicate damage from detonation which can collapse the ring lands and stick a piston in the hole. Now the rod's ability to move has been compromised. Maybe to the extent of bending a wrist pin....Boom!! It will happen in an instant with no real warning.
Any chance of a low oil level in the engine?!? Are you running a "Catch Can" to keep hot oil fumes out of the intake!?
Picturs of pistons SrtDub!?!? You did state no FI on the engine correct!?!
Thanks
Cheers!